CBD For Stress – Anxiolytic and Anxiolytic Effects
Facts about cbd oil for stress is a natural way to combat daily stressors that can lead to chronic health problems. CBD can help calm the mind and body by reducing anxiety, insomnia, and depression. It can also reduce pain caused by fibromyalgia and other conditions. It can also be used to treat anxiety disorders such as social anxiety disorder, PTSD, panic disorder, and obsessive-compulsive disorder.
CBD for Stress Relief: A Natural Approach to Finding Calm
CBD has been shown to have anxiolytic effects in animal models using the elevated plus maze (EPM) and Vogel conflict test (VCT). In these studies, CBD produced anxiolytic effects at moderate but not high doses, revealing a bell-shaped dose-response curve. The anxiolytic effect of CBD was mediated by 5-HT1AR receptor activation in the basolateral amygdala (BNST) and prelimbic cortex. In addition, fMRI experiments using a fearful faces task showed that CBD decreased blood-oxygen-level dependent activation of the amygdala and anterior cingulate cortex, and reduced amplitude of skin conductance responses.
Clinical trials have also shown that CBD reduces physiological stress responses in healthy individuals, including a simulated public speaking test. Moreover, double-blind placebo controlled clinical trials of people with social anxiety disorder have demonstrated that 400–600 mg of CBD per day significantly reduces subjective symptoms of anxiety in these individuals. Further, CBD was found to enhance extinction and inhibit reconsolidation of fear memory, suggesting potential for PTSD treatment.
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